Designed and prototyped a closed-loop pressure control system for a VA-ECMO heart pump

Background

For our Senior Design Capstone, my team worked with cardiologist Dr. Kay Everett at Tufts Medical Center to explore improvements to the VA-ECMO heart pump system used for patients with end-stage heart failure. These pumps currently operate open-loop, requiring hospital staff to manually adjust pump speed in response to dangerous pressure changes. The goal of this project was to demonstrate the feasibility of closed-loop feedback control using a mock ECMO circuit with water. Our system detected simulated high-pressure events and automatically adjusted pump speed to restore pressure to a safe range.

Outcomes

  • The system detected high-pressure events via a pressure transducer and used PID control to adjust pump speed, stabilizing blood pressure

  • Developed a system that accurately modeled key characteristics of the human circulatory system, including Reynolds number and Pressure Recovery Coefficient

  1. Water Reservoir Tank

  2. Open/Close Value

  3. Peristaltic Pump

  4. 24V Stepper Motor Driver

  5. Arduino

  6. Flow Restriction Valve

  7. T-valves

  8. Differential Pressure Transducer

Working Video

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